Addison disease is a hormonal disorder resulting from a severe or total deficiency of the hormones made in the adrenal cortex. The adrenal cortex is the outer portion of the adrenal gland, of which there are two, located above each kidney. Two important hormones made by the adrenal cortex are cortisol and aldosterone. They are both essential for the normal functioning of the body. In particular, aldosterone regulates salt and water levels which affect blood volume and blood pressure. Nowadays, the major cause is an autoimmune disorder in which the body's immune system makes antibodies which attack the cells of the adrenal cortex and slowly destroys them. This can take months to years. #addisonsdisease #addison #autoimmunedisease #immunesystem #immunity #dryskin #hyperpigmentation #skincare #health #foryou #foryoupage #fyp