Replying to @kavaking999 This is not fear mongering it's reporting the studies. As mentioned you can find studies to support both sides, at the end of most of these papers the authors agree we need long term safety studies, which we currently don't have. This is just me reporting the information and formulating my own opinion, you do you! Reference: Huang, J., et al. (2017). “Potential toxicity of nano-hydroxyapatite particles in mammalian cells.” Toxicology Research, 6(3), 332–339.  Fadeel, B., et al. (2018). “Nanotoxicology: a clinical perspective.” Nanotoxicology, 12(1), 1–4.   Yu, W., et al. (2019). “Toxicity of hydroxyapatite nanoparticles: an updated review.” Colloids and Surfaces B: Biointerfaces, 175, 728–739.  Kaneko, K., et al. (2022). Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug) - but how? PLOS ONE, 17(5), e0268067.  Laurenti, M., et al. (2019). Biological response to hydroxyapatite nanoparticles: New insights on controlling cell behavior. Frontiers in Bioengineering and Biotechnology, 7, 307.  Misra, S. K., et al. (2012). Nanoparticles in tissue engineering: A case study of hydroxyapatite nanoparticles in bone regeneration. Nanotoxicology, 6(6), 774-784.  #toothpaste #oralhealth #oralcare #oralhygiene #toxinfree #nontoxic #holistichealth #gurunanda @Puneet Nanda bridge the gap